BDBM11776 2-{[(2-chlorophenyl)methyl][3-(trifluoromethyl)benzene]sulfonamido}-N-hydroxypropanamide::hydroxamate deriv. B22

SMILES: CC(N(Cc1ccccc1Cl)S(=O)(=O)c1cccc(c1)C(F)(F)F)C(=O)NO

InChI Key: InChIKey=LIEXKGDUVKULCK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11776   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase (ChC) (Clostridium histolyticum)	BDBM11776 (2-{[(2-chlorophenyl)methyl][3-(trifluoromethyl)ben...) Show SMILES CC(N(Cc1ccccc1Cl)S(=O)(=O)c1cccc(c1)C(F)(F)F)C(=O)NO Show InChI InChI=1S/C17H16ClF3N2O4S/c1-11(16(24)22-25)23(10-12-5-2-3-8-15(12)18)28(26,27)14-7-4-6-13(9-14)17(19,20)21/h2-9,11,25H,10H2,1H3,(H,22,24)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze					Assay Description The rate of hydrolysis was determined from the change in absorbance at 324 nm using an extinction coefficient, 24700 M-1 cm-1 for FALGPA. Initial vel...				Bioorg Med Chem 8: 637-45 (2000) Article DOI: 10.1016/s0968-0896(99)00316-8 BindingDB Entry DOI: 10.7270/Q2542KT3
					More data for this Ligand-Target Pair