BDBM11786 2-{[(2-chlorophenyl)methyl][5-(dimethylamino)naphthalene-1-]sulfonamido}-N-hydroxypropanamide::hydroxamate deriv. B32

SMILES: CC(N(Cc1ccccc1Cl)S(=O)(=O)c1cccc2c(cccc12)N(C)C)C(=O)NO

InChI Key: InChIKey=CHXSTFRHFFMWAQ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11786   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase (ChC) (Clostridium histolyticum)	BDBM11786 (2-{[(2-chlorophenyl)methyl][5-(dimethylamino)napht...) Show SMILES CC(N(Cc1ccccc1Cl)S(=O)(=O)c1cccc2c(cccc12)N(C)C)C(=O)NO Show InChI InChI=1S/C22H24ClN3O4S/c1-15(22(27)24-28)26(14-16-8-4-5-11-19(16)23)31(29,30)21-13-7-9-17-18(21)10-6-12-20(17)25(2)3/h4-13,15,28H,14H2,1-3H3,(H,24,27)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze					Assay Description The rate of hydrolysis was determined from the change in absorbance at 324 nm using an extinction coefficient, 24700 M-1 cm-1 for FALGPA. Initial vel...				Bioorg Med Chem 8: 637-45 (2000) Article DOI: 10.1016/s0968-0896(99)00316-8 BindingDB Entry DOI: 10.7270/Q2542KT3
					More data for this Ligand-Target Pair