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SMILES: CC(C)c1cn(nn1)-c1c[nH]n(-c2ccc(CO)cn2)c1=O

InChI Key: InChIKey=CRLFGLQKSFFTDZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 118333   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM118333
PNG
(US8653111, 45)
Show SMILES CC(C)c1cn(nn1)-c1c[nH]n(-c2ccc(CO)cn2)c1=O
Show InChI InChI=1S/C14H16N6O2/c1-9(2)11-7-19(18-17-11)12-6-16-20(14(12)22)13-4-3-10(8-21)5-15-13/h3-7,9,16,21H,8H2,1-2H3
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n/an/a 780n/an/an/an/an/an/a



Bayer Intellectual Property GmbH

US Patent


Assay Description
Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...

US Patent US8653111 (2014)


BindingDB Entry DOI: 10.7270/Q2GH9GMD
More data for this
Ligand-Target Pair