BDBM119217 US8673938, 75
SMILES: CCSc1nc(ccc1C(=O)NC1C2CC3CC(C2)CC1C3)N1C[C@H]2[C@@H](C1)[C@@H]2C(O)=O
InChI Key: InChIKey=WUYAHJJXCBDIKJ-NCIKYPDZSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human)) | BDBM119217 (US8673938, 75) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti... | US Patent US8673938 (2014) BindingDB Entry DOI: 10.7270/Q2610Z0D | |||||||||||
More data for this Ligand-Target Pair |