BDBM119442 US8685986, 17
SMILES: ONC(=O)c1ccc(CNC(=O)c2[nH]c(cc2-c2ccc(F)cc2)-c2ccccc2)o1
InChI Key: InChIKey=PRGIDXCMQOBJCD-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM119442 (US8685986, 17) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.5 | -12.2 | n/a | n/a | n/a | n/a | n/a | 6.0 | 30 |
Ube Industries, Ltd. US Patent | Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (... | US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1 | |||||||||||
More data for this Ligand-Target Pair |