BDBM119683 US8680116, 1-48

SMILES: O=c1[nH]c2ccc(cc2c(OCc2ccccn2)c1-c1cccs1)-c1ccncc1

InChI Key: InChIKey=YUXSKNMEPLBNMX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 119683   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM119683 (US8680116, 1-48) Show SMILES O=c1[nH]c2ccc(cc2c(OCc2ccccn2)c1-c1cccs1)-c1ccncc1 Show InChI InChI=1S/C24H17N3O2S/c28-24-22(21-5-3-13-30-21)23(29-15-18-4-1-2-10-26-18)19-14-17(6-7-20(19)27-24)16-8-11-25-12-9-16/h1-14H,15H2,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...				US Patent US8680116 (2014) BindingDB Entry DOI: 10.7270/Q2N29VM1
					More data for this Ligand-Target Pair