BDBM119867 5‐chloro‐2‐[2‐chloro‐4‐(1,2,3‐triazol‐1‐ ylmethyl)phenoxy]phenol (24)

SMILES: Oc1cc(Cl)ccc1Oc1ccc(Cn2ccnn2)cc1Cl

InChI Key: InChIKey=URYLBENRERBXMY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 119867   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Enoyl-acyl carrier reductase (Toxoplasma gondii)	BDBM119867 (5‐chloro‐2‐[2‐chloro‐...) Show SMILES Oc1cc(Cl)ccc1Oc1ccc(Cn2ccnn2)cc1Cl Show InChI InChI=1S/C15H11Cl2N3O2/c16-11-2-4-15(13(21)8-11)22-14-3-1-10(7-12(14)17)9-20-6-5-18-19-20/h1-8,21H,9H2	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	7.5	n/a
Johns Hopkins Bloomberg School of Public Health					Assay Description The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...				Biochemistry 52: 9155-66 (2013) Article DOI: 10.1021/bi400945y BindingDB Entry DOI: 10.7270/Q2PV6J27
					More data for this Ligand-Target Pair