BDBM119870 N‐{[3‐chloro‐4‐(4‐chloro‐2‐ hydroxyphenoxy)phenyl]methyl}‐2‐(3‐methyl‐1,2‐ oxazol‐5‐yl)acetamide (28)

SMILES: Cc1cc(CC(=O)NCc2ccc(Oc3ccc(Cl)cc3O)c(Cl)c2)on1

InChI Key: InChIKey=ANHCXYXPDOSJLT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 119870   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Enoyl-acyl carrier reductase ENR (Toxoplasma gondii)	BDBM119870 (N‐{[3‐chloro‐4‐(4‐ch...) Show SMILES Cc1cc(CC(=O)NCc2ccc(Oc3ccc(Cl)cc3O)c(Cl)c2)on1 Show InChI InChI=1S/C19H16Cl2N2O4/c1-11-6-14(27-23-11)9-19(25)22-10-12-2-4-17(15(21)7-12)26-18-5-3-13(20)8-16(18)24/h2-8,24H,9-10H2,1H3,(H,22,25)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	7.5	n/a
Johns Hopkins Bloomberg School of Public Health					Assay Description The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...				Biochemistry 52: 9155-66 (2013) Article DOI: 10.1021/bi400945y BindingDB Entry DOI: 10.7270/Q2PV6J27
					More data for this Ligand-Target Pair