BDBM11990 4-(5-{[(3E)-5-cyano-2-hydroxy-4-methyl-6-oxo-3,6-dihydropyridin-3-ylidene]methyl}furan-2-yl)benzene-1-sulfonamide::chemical diversity library compound 15

SMILES: NS(=O)(=O)c1ccc(cc1)-c1ccc(C=c2c(=O)[nH]c(O)c(C#N)c2=C)o1

InChI Key: InChIKey=ARTWDZADTHIUKE-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11990   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Anthrax Lethal Factor (LF) (Bacillus anthracis)	BDBM11990 (4-(5-{[(3E)-5-cyano-2-hydroxy-4-methyl-6-oxo-3,6-d...) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1ccc(C=c2c(=O)[nH]c(O)c(C#N)c2=C)o1 |w:14.14| Show InChI InChI=1S/C18H13N3O5S/c1-10-14(17(22)21-18(23)15(10)9-19)8-12-4-7-16(26-12)11-2-5-13(6-3-11)27(20,24)25/h2-8,23H,1H2,(H,21,22)(H2,20,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.40E+3	-7.23	1.08E+4	n/a	n/a	n/a	n/a	7.2	27
Montana State University					Assay Description For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...				J Med Chem 49: 5232-44 (2006) Article DOI: 10.1021/jm0605132 BindingDB Entry DOI: 10.7270/Q20C4T19
					More data for this Ligand-Target Pair