null

SMILES: CN1CCc2ccc(NC(=O)c3cccc(CNC(=O)c4cc5ccc(cc5[nH]4)C(N)=O)c3)cc2C1

InChI Key: InChIKey=OGBCEWLJMNHRGZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 119925   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM119925 (US8697911, 54) Show SMILES CN1CCc2ccc(NC(=O)c3cccc(CNC(=O)c4cc5ccc(cc5[nH]4)C(N)=O)c3)cc2C1 Show InChI InChI=1S/C28H27N5O3/c1-33-10-9-18-7-8-23(12-22(18)16-33)31-27(35)21-4-2-3-17(11-21)15-30-28(36)25-13-19-5-6-20(26(29)34)14-24(19)32-25/h2-8,11-14,32H,9-10,15-16H2,1H3,(H2,29,34)(H,30,36)(H,31,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.450	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US8697911 (2014) BindingDB Entry DOI: 10.7270/Q25X27KR
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM119925 (US8697911, 54) Show SMILES CN1CCc2ccc(NC(=O)c3cccc(CNC(=O)c4cc5ccc(cc5[nH]4)C(N)=O)c3)cc2C1 Show InChI InChI=1S/C28H27N5O3/c1-33-10-9-18-7-8-23(12-22(18)16-33)31-27(35)21-4-2-3-17(11-21)15-30-28(36)25-13-19-5-6-20(26(29)34)14-24(19)32-25/h2-8,11-14,32H,9-10,15-16H2,1H3,(H2,29,34)(H,30,36)(H,31,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	7.5	28
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase is measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-luc...				US Patent US8697911 (2014) BindingDB Entry DOI: 10.7270/Q25X27KR
					More data for this Ligand-Target Pair