BDBM119964 US8697911, 128

SMILES: CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(CNC(=O)c4ccc(s4)-c4cnco4)c3)sc2C1

InChI Key: InChIKey=AGAUQMZZBQFDGW-KRWDZBQOSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 119964   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM119964 (US8697911, 128) Show SMILES CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(CNC(=O)c4ccc(s4)-c4cnco4)c3)sc2C1 |r| Show InChI InChI=1S/C25H25N5O3S2/c1-30(2)17-6-7-18-22(11-17)35-25(28-18)29-23(31)16-5-3-4-15(10-16)12-27-24(32)21-9-8-20(34-21)19-13-26-14-33-19/h3-5,8-10,13-14,17H,6-7,11-12H2,1-2H3,(H,27,32)(H,28,29,31)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.370	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US8697911 (2014) BindingDB Entry DOI: 10.7270/Q25X27KR
					More data for this Ligand-Target Pair