null
SMILES: O=C(NCc1cccc(c1)C(=O)Nc1nc2CC[C@@H](Cc2s1)N1CCOCC1)c1ccc(cc1)-c1cnco1
InChI Key: InChIKey=HJFVYDJAEFHGGT-QHCPKHFHSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM119982 (US8697911, 162) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.430 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices... | US Patent US8697911 (2014) BindingDB Entry DOI: 10.7270/Q25X27KR | |||||||||||
More data for this Ligand-Target Pair |