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SMILES: Cc1nnn(c1COc1cc(C(=O)NC2CCOCC2)n(C)n1)-c1ccc(F)cc1

InChI Key: InChIKey=UDZMIXHTMJAVCK-UHFFFAOYSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120146   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gamma-aminobutyric acid receptor subunit alpha-5


(Homo sapiens (Human))		BDBM120146
PNG
(US8697696, 3)
Show SMILES Cc1nnn(c1COc1cc(C(=O)NC2CCOCC2)n(C)n1)-c1ccc(F)cc1
Show InChI InChI=1S/C20H23FN6O3/c1-13-18(27(25-23-13)16-5-3-14(21)4-6-16)12-30-19-11-17(26(2)24-19)20(28)22-15-7-9-29-10-8-15/h3-6,11,15H,7-10,12H2,1-2H3,(H,22,28)
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Similars
US Patent
 15.7 -9.89n/an/an/an/an/a7.54



Roche Palo Alto LLC

US Patent


Assay Description
Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell membranes, [3H]flumazenil at a conc...

US Patent US8697696 (2014)


BindingDB Entry DOI: 10.7270/Q2DB80HJ
More data for this
Ligand-Target Pair