BDBM120152 US8697696, 9

SMILES: CC(C)NC(=O)c1sc(\C=C\c2c(C)nnn2-c2ccc(F)cc2)nc1C

InChI Key: InChIKey=QGOIQUQFLOHODO-MDZDMXLPSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120152   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-5 (GABA(A)) (Homo sapiens (Human))	BDBM120152 (US8697696, 9) Show SMILES CC(C)NC(=O)c1sc(\C=C\c2c(C)nnn2-c2ccc(F)cc2)nc1C Show InChI InChI=1S/C19H20FN5OS/c1-11(2)21-19(26)18-13(4)22-17(27-18)10-9-16-12(3)23-24-25(16)15-7-5-14(20)6-8-15/h5-11H,1-4H3,(H,21,26)/b10-9+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.80	-10.4	n/a	n/a	n/a	n/a	n/a	7.5	4
Roche Palo Alto LLC US Patent					Assay Description Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell membranes, [3H]flumazenil at a conc...				US Patent US8697696 (2014) BindingDB Entry DOI: 10.7270/Q2DB80HJ
					More data for this Ligand-Target Pair