BDBM120301 US8703811, 40::US8703811, 41
SMILES: Cc1nc2cc(Cl)ccc2n1-c1ccc(s1)C(=O)NC1CC1
InChI Key: InChIKey=QOOWBQNDIMAUDB-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum) | BDBM120301 (US8703811, 40 | US8703811, 41) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College US Patent | Assay Description Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al... | US Patent US8703811 (2014) BindingDB Entry DOI: 10.7270/Q2WD3Z7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum) | BDBM120301 (US8703811, 40 | US8703811, 41) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College US Patent | Assay Description Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al... | US Patent US8703811 (2014) BindingDB Entry DOI: 10.7270/Q2WD3Z7P | |||||||||||
More data for this Ligand-Target Pair |