null
SMILES: Clc1ccc(NC(=O)Nc2ccc(cc2)C(=O)\C=C\c2ccc3OCOc3c2)cc1
InChI Key: InChIKey=XHEJGOZBLJQDOZ-QQDOKKFESA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Falcipain-2 (Plasmodium falciparum) | BDBM12032 (1-{4-[(2E)-3-(2H-1,3-benzodioxol-5-yl)prop-2-enoyl...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | 5.5 | 22 |
Universidad Central de Venezuela | Assay Description The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy... | J Med Chem 48: 3654-8 (2005) Article DOI: 10.1021/jm058208o BindingDB Entry DOI: 10.7270/Q2GF0RRD | |||||||||||
More data for this Ligand-Target Pair |