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SMILES: Cc1cccc(c1-c1ccccc1)S(=O)(=O)N[C@@H](CC(O)=O)C=O

InChI Key: InChIKey=DUKWIKJCKVNLHC-AWEZNQCLSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12049   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Caspase-1


(Homo sapiens (Human))		BDBM12049
PNG
((3S)-3-[(3-methyl-2-phenylbenzene)sulfonamido]-4-o...)
Show SMILES Cc1cccc(c1-c1ccccc1)S(=O)(=O)N[C@@H](CC(O)=O)C=O |r|
Show InChI InChI=1S/C17H17NO5S/c1-12-6-5-9-15(17(12)13-7-3-2-4-8-13)24(22,23)18-14(11-19)10-16(20)21/h2-9,11,14,18H,10H2,1H3,(H,20,21)/t14-/m0/s1
PDB
MMDB

NCI pathway
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KEGG

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UniChem

Similars
Article
PubMed
 1.90E+3 -8.11n/an/an/an/an/a7.037



Pfizer



Assay Description
The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...

Bioorg Med Chem 10: 31-40 (2002)


Article DOI: 10.1016/s0968-0896(01)00250-4
BindingDB Entry DOI: 10.7270/Q2BP011G
More data for this
Ligand-Target Pair