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BDBM120827 N-formyl-5-(-2'-nitrophenyl)-3-phenylpyrazoline (1h)

SMILES: [O-][N+](=O)c1ccccc1C1CC(=NN1C=O)c1ccccc1

InChI Key: InChIKey=PZTBCSIDLDFAQN-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 120827   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cathepsin B


(Capra hircus (Goat))
BDBM120827
PNG
(N-formyl-5-(-2'-nitrophenyl)-3-phenylpyrazolin...)
Show SMILES [O-][N+](=O)c1ccccc1C1CC(=NN1C=O)c1ccccc1 |c:12|
Show InChI InChI=1S/C16H13N3O3/c20-11-18-16(13-8-4-5-9-15(13)19(21)22)10-14(17-18)12-6-2-1-3-7-12/h1-9,11,16H,10H2
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
0.141 -14.0n/an/an/an/an/a6.037



Kurukshetra University



Assay Description
Enzyme was equilibrated in 0.1 M phosphate buffer, pH 6.0 at 37 °C. All compounds were prepared in DMSO. Various concentrations of compounds we...


Bioorg Chem 57: 43-50 (2014)


Article DOI: 10.1016/j.bioorg.2014.07.012
BindingDB Entry DOI: 10.7270/Q26Q1VXJ
More data for this
Ligand-Target Pair
Cathepsin H


(Capra hircus (Goat))
BDBM120827
PNG
(N-formyl-5-(-2'-nitrophenyl)-3-phenylpyrazolin...)
Show SMILES [O-][N+](=O)c1ccccc1C1CC(=NN1C=O)c1ccccc1 |c:12|
Show InChI InChI=1S/C16H13N3O3/c20-11-18-16(13-8-4-5-9-15(13)19(21)22)10-14(17-18)12-6-2-1-3-7-12/h1-9,11,16H,10H2
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
0.963 -12.8n/an/an/an/an/a6.037



Kurukshetra University



Assay Description
Enzyme was equilibrated in 0.1 M phosphate buffer, pH 6.0 at 37 °C. All compounds were prepared in DMSO. Various concentrations of compounds we...


Bioorg Chem 57: 43-50 (2014)


Article DOI: 10.1016/j.bioorg.2014.07.012
BindingDB Entry DOI: 10.7270/Q26Q1VXJ
More data for this
Ligand-Target Pair