BDBM120844 US8716478, D230::US8716478, D238::US9499570, D230

SMILES: CC(C)OCCOc1nc(Oc2ccc3B(O)OCc3c2)c(Cl)cc1C#N

InChI Key: InChIKey=BKBBEYMNJXXDAQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 120844   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM120844 (US8716478, D230 | US8716478, D238 | US9499570, D23...) Show SMILES CC(C)OCCOc1nc(Oc2ccc3B(O)OCc3c2)c(Cl)cc1C#N Show InChI InChI=1S/C18H18BClN2O5/c1-11(2)24-5-6-25-17-12(9-21)8-16(20)18(22-17)27-14-3-4-15-13(7-14)10-26-19(15)23/h3-4,7-8,11,23H,5-6,10H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.20	n/a	n/a	n/a	n/a	7.5	n/a
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...				US Patent US9499570 (2016) BindingDB Entry DOI: 10.7270/Q2CZ363N
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM120844 (US8716478, D230 | US8716478, D238 | US9499570, D23...) Show SMILES CC(C)OCCOc1nc(Oc2ccc3B(O)OCc3c2)c(Cl)cc1C#N Show InChI InChI=1S/C18H18BClN2O5/c1-11(2)24-5-6-25-17-12(9-21)8-16(20)18(22-17)27-14-3-4-15-13(7-14)10-26-19(15)23/h3-4,7-8,11,23H,5-6,10H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.20	n/a	n/a	n/a	n/a	7.5	37
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...				US Patent US8716478 (2014) BindingDB Entry DOI: 10.7270/Q2Z60MQ7
					More data for this Ligand-Target Pair