BDBM12095 3-(2-phenylacetamido)-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-5-carboxamide::3-Amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole 13

SMILES: NC(=O)N1Cc2n[nH]c(NC(=O)Cc3ccccc3)c2C1

InChI Key: InChIKey=AMPGTDPLFIQJLI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12095   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM12095 (3-(2-phenylacetamido)-1H,4H,5H,6H-pyrrolo[3,4-c]py...) Show SMILES NC(=O)N1Cc2n[nH]c(NC(=O)Cc3ccccc3)c2C1 Show InChI InChI=1S/C14H15N5O2/c15-14(21)19-7-10-11(8-19)17-18-13(10)16-12(20)6-9-4-2-1-3-5-9/h1-5H,6-8H2,(H2,15,21)(H2,16,17,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences					Assay Description The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...				Bioorg Med Chem Lett 16: 1084-90 (2006) Article DOI: 10.1016/j.bmcl.2005.10.071 BindingDB Entry DOI: 10.7270/Q2PZ5725
					More data for this Ligand-Target Pair
Cyclin-Dependent Kinase 2 (CDK2) (Homo sapiens (Human))	BDBM12095 (3-(2-phenylacetamido)-1H,4H,5H,6H-pyrrolo[3,4-c]py...) Show SMILES NC(=O)N1Cc2n[nH]c(NC(=O)Cc3ccccc3)c2C1 Show InChI InChI=1S/C14H15N5O2/c15-14(21)19-7-10-11(8-19)17-18-13(10)16-12(20)6-9-4-2-1-3-5-9/h1-5H,6-8H2,(H2,15,21)(H2,16,17,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	7.4	22
Nerviano Medical Sciences					Assay Description The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...				Bioorg Med Chem Lett 16: 1084-90 (2006) Article DOI: 10.1016/j.bmcl.2005.10.071 BindingDB Entry DOI: 10.7270/Q2PZ5725
					More data for this Ligand-Target Pair