BDBM121070 US8722896, (-)-(3R)-1-(2-Methoxybenzyl)- N-(9-fluoro-3,4-dihydro-2H-1,5- benzodioxepin-7-ylmethyl)-N- isobutylpyrrolidine-3- carboxamide
SMILES: COc1ccccc1CN1CC[C@H](C1)C(=O)N(CC(C)C)Cc1cc(F)c2OCCCOc2c1
InChI Key: InChIKey=LWIUAAFMSATBNR-JOCHJYFZSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prokineticin receptor 2 (PRK2) (Cricetulus griseus (Chinese hamster)) | BDBM121070 (US8722896, (-)-(3R)-1-(2-Methoxybenzyl)- N-(9-fluo...) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.810 | -12.9 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
The Regents of the University of California US Patent | Assay Description An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65... | US Patent US8722896 (2014) BindingDB Entry DOI: 10.7270/Q29G5KGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prokineticin receptor 2 (PRK2) (Cricetulus griseus (Chinese hamster)) | BDBM121070 (US8722896, (-)-(3R)-1-(2-Methoxybenzyl)- N-(9-fluo...) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.70 | -12.4 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
The Regents of the University of California US Patent | Assay Description An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65... | US Patent US8722896 (2014) BindingDB Entry DOI: 10.7270/Q29G5KGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prokineticin receptor 1 (PRK1) (Cricetulus griseus (Chinese hamster)) | BDBM121070 (US8722896, (-)-(3R)-1-(2-Methoxybenzyl)- N-(9-fluo...) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 10.4 | -11.3 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
The Regents of the University of California US Patent | Assay Description An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65... | US Patent US8722896 (2014) BindingDB Entry DOI: 10.7270/Q29G5KGF | |||||||||||
More data for this Ligand-Target Pair |