BDBM121088 US8722896, (-)-(3R)-1-(3-Methoxybenzyl)- N-(9-chloro-3,4-dihydro-2H-1,5- benzodioxepin-7-ylmethyl)-N- isobutylpyrrolidine-3- carboxamide

SMILES: COc1cccc(CN2CC[C@H](C2)C(=O)N(CC(C)C)Cc2cc(Cl)c3OCCCOc3c2)c1

InChI Key: InChIKey=NAJXUGYEBJEJQC-JOCHJYFZSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 121088   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 2 (PRK2) (Cricetulus griseus (Chinese hamster))	BDBM121088 (US8722896, (-)-(3R)-1-(3-Methoxybenzyl)- N-(9-chlo...) Show SMILES COc1cccc(CN2CC[C@H](C2)C(=O)N(CC(C)C)Cc2cc(Cl)c3OCCCOc3c2)c1 |r| Show InChI InChI=1S/C27H35ClN2O4/c1-19(2)15-30(17-21-13-24(28)26-25(14-21)33-10-5-11-34-26)27(31)22-8-9-29(18-22)16-20-6-4-7-23(12-20)32-3/h4,6-7,12-14,19,22H,5,8-11,15-18H2,1-3H3/t22-/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.03	-12.7	n/a	n/a	n/a	n/a	n/a	n/a	37
The Regents of the University of California US Patent					Assay Description An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...				US Patent US8722896 (2014) BindingDB Entry DOI: 10.7270/Q29G5KGF
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (PRK1) (Cricetulus griseus (Chinese hamster))	BDBM121088 (US8722896, (-)-(3R)-1-(3-Methoxybenzyl)- N-(9-chlo...) Show SMILES COc1cccc(CN2CC[C@H](C2)C(=O)N(CC(C)C)Cc2cc(Cl)c3OCCCOc3c2)c1 |r| Show InChI InChI=1S/C27H35ClN2O4/c1-19(2)15-30(17-21-13-24(28)26-25(14-21)33-10-5-11-34-26)27(31)22-8-9-29(18-22)16-20-6-4-7-23(12-20)32-3/h4,6-7,12-14,19,22H,5,8-11,15-18H2,1-3H3/t22-/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	-11.9	n/a	n/a	n/a	n/a	n/a	n/a	37
The Regents of the University of California US Patent					Assay Description An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...				US Patent US8722896 (2014) BindingDB Entry DOI: 10.7270/Q29G5KGF
					More data for this Ligand-Target Pair