BDBM121156 US8722896, (+/-)-2-Methyl-3-(1-((2- methoxypyridin-3- ylmethyl)amino)-N-(9- chloro-3,4-dihydro-2H-1,5- benzodioxepin-7-ylmethyl)-N- isobutylpropanamide

SMILES: COc1ncccc1CNCC(C)C(=O)N(CC(C)C)Cc1cc(Cl)c2OCCCOc2c1

InChI Key: InChIKey=AJVTYHYPVKOHDL-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 121156   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 2 (PRK2) (Cricetulus griseus (Chinese hamster))	BDBM121156 (US8722896, (+/-)-2-Methyl-3-(1-((2- methoxypyridin...) Show SMILES COc1ncccc1CNCC(C)C(=O)N(CC(C)C)Cc1cc(Cl)c2OCCCOc2c1 Show InChI InChI=1S/C25H34ClN3O4/c1-17(2)15-29(16-19-11-21(26)23-22(12-19)32-9-6-10-33-23)25(30)18(3)13-27-14-20-7-5-8-28-24(20)31-4/h5,7-8,11-12,17-18,27H,6,9-10,13-16H2,1-4H3	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.06	-12.7	n/a	n/a	n/a	n/a	n/a	n/a	37
The Regents of the University of California US Patent					Assay Description An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...				US Patent US8722896 (2014) BindingDB Entry DOI: 10.7270/Q29G5KGF
					More data for this Ligand-Target Pair
Prokineticin receptor 2 (PRK2) (Cricetulus griseus (Chinese hamster))	BDBM121156 (US8722896, (+/-)-2-Methyl-3-(1-((2- methoxypyridin...) Show SMILES COc1ncccc1CNCC(C)C(=O)N(CC(C)C)Cc1cc(Cl)c2OCCCOc2c1 Show InChI InChI=1S/C25H34ClN3O4/c1-17(2)15-29(16-19-11-21(26)23-22(12-19)32-9-6-10-33-23)25(30)18(3)13-27-14-20-7-5-8-28-24(20)31-4/h5,7-8,11-12,17-18,27H,6,9-10,13-16H2,1-4H3	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.82	-12.4	n/a	n/a	n/a	n/a	n/a	n/a	37
The Regents of the University of California US Patent					Assay Description An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...				US Patent US8722896 (2014) BindingDB Entry DOI: 10.7270/Q29G5KGF
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (PRK1) (Cricetulus griseus (Chinese hamster))	BDBM121156 (US8722896, (+/-)-2-Methyl-3-(1-((2- methoxypyridin...) Show SMILES COc1ncccc1CNCC(C)C(=O)N(CC(C)C)Cc1cc(Cl)c2OCCCOc2c1 Show InChI InChI=1S/C25H34ClN3O4/c1-17(2)15-29(16-19-11-21(26)23-22(12-19)32-9-6-10-33-23)25(30)18(3)13-27-14-20-7-5-8-28-24(20)31-4/h5,7-8,11-12,17-18,27H,6,9-10,13-16H2,1-4H3	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	44.8	-10.4	n/a	n/a	n/a	n/a	n/a	n/a	37
The Regents of the University of California US Patent					Assay Description An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...				US Patent US8722896 (2014) BindingDB Entry DOI: 10.7270/Q29G5KGF
					More data for this Ligand-Target Pair