BDBM121480 US8722683, 27
SMILES: CC(C)(O)CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1
InChI Key: InChIKey=RWYJJIZNTJVITE-WGSAOQKQSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM121480 (US8722683, 27) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann LA-Roche Inc. US Patent | Assay Description Aliquots of membrane preparations were thawed at RT, resupended in assay buffer (D2, D3: 50 mM Tris-HCl, 120 mM NaCl, 5 mM MgCl2, 1 mM EDTA, 5 mM KCl... | US Patent US8722683 (2014) BindingDB Entry DOI: 10.7270/Q2J101VJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM121480 (US8722683, 27) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 22.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann LA-Roche Inc. US Patent | Assay Description Aliquots of membrane preparations were thawed at RT, resupended in assay buffer (D2, D3: 50 mM Tris-HCl, 120 mM NaCl, 5 mM MgCl2, 1 mM EDTA, 5 mM KCl... | US Patent US8722683 (2014) BindingDB Entry DOI: 10.7270/Q2J101VJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM121480 (US8722683, 27) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 76.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann LA-Roche Inc. US Patent | Assay Description Aliquots of membrane preparations were thawed at RT, resupended in assay buffer (D2, D3: 50 mM Tris-HCl, 120 mM NaCl, 5 mM MgCl2, 1 mM EDTA, 5 mM KCl... | US Patent US8722683 (2014) BindingDB Entry DOI: 10.7270/Q2J101VJ | |||||||||||
More data for this Ligand-Target Pair |