BDBM121543 US8729273, 13

SMILES: Cc1nn(cc1C(O)=O)-c1ccc2n(CC3CC3)cc(C#N)c2c1

InChI Key: InChIKey=FJLOXIFWHOUVKH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 121543   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM121543 (US8729273, 13) Show SMILES Cc1nn(cc1C(O)=O)-c1ccc2n(CC3CC3)cc(C#N)c2c1 Show InChI InChI=1S/C18H16N4O2/c1-11-16(18(23)24)10-22(20-11)14-4-5-17-15(6-14)13(7-19)9-21(17)8-12-2-3-12/h4-6,9-10,12H,2-3,8H2,1H3,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
LG Life Sciences Ltd. US Patent					Assay Description Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...				US Patent US8729273 (2014) BindingDB Entry DOI: 10.7270/Q2D79937
					More data for this Ligand-Target Pair