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SMILES: CCCCc1cc(cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1)C(=O)N(C)C

InChI Key: InChIKey=GMZNPEVSWOSGIT-AREMUKBSSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123087   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM123087
PNG
(US8742115, 27)
Show SMILES CCCCc1cc(cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1)C(=O)N(C)C |r|
Show InChI InChI=1S/C30H40ClN5O3/c1-5-6-7-23-17-22(30(39)34(3)4)18-27(32-23)33-29(38)26-10-11-28(37)36(26)24-12-14-35(15-13-24)19-21-8-9-25(31)20(2)16-21/h8-9,16-18,24,26H,5-7,10-15,19H2,1-4H3,(H,32,33,38)/t26-/m1/s1
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Similars
US Patent
 414n/an/an/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The CCR3 receptor binding assay was performed in a Scintillation Proximity Assay (SPA) design with the radioligand recombinant human 125Iodine-eotaxi...

US Patent US8742115 (2014)


BindingDB Entry DOI: 10.7270/Q2V986QD
More data for this
Ligand-Target Pair