BDBM123143 US8742113, 157

SMILES: CC(C)OC(=O)C1C(OC(=Cc2c[nH]c3ncccc23)C1=O)=Nc1ccc(OCCO)cc1C

InChI Key: InChIKey=VCDRBUPPCUYQED-MKDICFJNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123143   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM123143 (US8742113, 157) Show SMILES CC(C)OC(=O)C1C(OC(=Cc2c[nH]c3ncccc23)C1=O)=Nc1ccc(OCCO)cc1C |w:10.10,22.25| Show InChI InChI=1S/C25H25N3O6/c1-14(2)33-25(31)21-22(30)20(12-16-13-27-23-18(16)5-4-8-26-23)34-24(21)28-19-7-6-17(11-15(19)3)32-10-9-29/h4-8,11-14,21,29H,9-10H2,1-3H3,(H,26,27)/b20-12-,28-24+	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
SBI Biotech Co., Ltd.; Carna Biosciences, Inc. US Patent					Assay Description Measurement of kinase activity was carried out using an MSA assay kit (QuickScout Screening Assist Kit, Carna Biosciences, Inc.). Assay buffer (20 mM...				US Patent US8742113 (2014) BindingDB Entry DOI: 10.7270/Q2B856S5
					More data for this Ligand-Target Pair