BDBM123240 US8742110, 4-4
SMILES: CCOc1ccc(c(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)c1)-c1ccc(F)c(F)c1
InChI Key: InChIKey=PPDSZBTULLWLDP-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Somatostatin receptor type 5 (Homo sapiens (Human)) | BDBM123240 (US8742110, 4-4) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.502 | n/a | n/a | n/a | n/a | 7.8 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et... | US Patent US8742110 (2014) BindingDB Entry DOI: 10.7270/Q26H4G39 | |||||||||||
More data for this Ligand-Target Pair |