BDBM123657 US8748618, LD-1-29 (or) AI-10-54

SMILES: CCOc1ccc2nc([nH]c2c1)-c1ccccn1

InChI Key: InChIKey=DOHRGJDYYQWTAN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123657   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Core-binding factor subunit beta (CBFB) (Homo sapiens (Human))	BDBM123657 (US8748618, LD-1-29 (or) AI-10-54) Show SMILES CCOc1ccc2nc([nH]c2c1)-c1ccccn1 Show InChI InChI=1S/C14H13N3O/c1-2-18-10-6-7-11-13(9-10)17-14(16-11)12-5-3-4-8-15-12/h3-9H,2H2,1H3,(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Patent Foundation US Patent					Assay Description We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...				US Patent US8748618 (2014) BindingDB Entry DOI: 10.7270/Q25M64C7
					More data for this Ligand-Target Pair