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BDBM123669 US8748618, AI-4-43

SMILES: Fc1cc2[nH]c(nc2c(F)c1F)-c1ccccn1

InChI Key: InChIKey=QFGZGWIKTOENCL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123669   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Core-binding factor subunit beta (CBFB)


(Homo sapiens (Human))
BDBM123669
PNG
(US8748618, AI-4-43)
Show SMILES Fc1cc2[nH]c(nc2c(F)c1F)-c1ccccn1
Show InChI InChI=1S/C12H6F3N3/c13-6-5-8-11(10(15)9(6)14)18-12(17-8)7-3-1-2-4-16-7/h1-5H,(H,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.40E+3n/an/an/an/an/an/a



University of Virginia Patent Foundation

US Patent


Assay Description
We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...


US Patent US8748618 (2014)


BindingDB Entry DOI: 10.7270/Q25M64C7
More data for this
Ligand-Target Pair