BDBM123676 US8748618, AI-10-88

SMILES: c1cn(cn1)-c1ccc2[nH]c(nc2c1)-c1ccccn1

InChI Key: InChIKey=JEWVUZWRPYNJEE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123676   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Core-binding factor subunit beta (CBFB) (Homo sapiens (Human))	BDBM123676 (US8748618, AI-10-88) Show SMILES c1cn(cn1)-c1ccc2[nH]c(nc2c1)-c1ccccn1 Show InChI InChI=1S/C15H11N5/c1-2-6-17-13(3-1)15-18-12-5-4-11(9-14(12)19-15)20-8-7-16-10-20/h1-10H,(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Patent Foundation US Patent					Assay Description We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...				US Patent US8748618 (2014) BindingDB Entry DOI: 10.7270/Q25M64C7
					More data for this Ligand-Target Pair