BDBM123678 US8748618, AI-10-96

SMILES: FC(F)(F)Oc1cc(-c2cccnc2)c2nc([nH]c2c1)-c1ccccn1

InChI Key: InChIKey=LZCLXSWMGVLSBC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123678   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Core-binding factor subunit beta (Homo sapiens (Human))	BDBM123678 (US8748618, AI-10-96) Show SMILES FC(F)(F)Oc1cc(-c2cccnc2)c2nc([nH]c2c1)-c1ccccn1 Show InChI InChI=1S/C18H11F3N4O/c19-18(20,21)26-12-8-13(11-4-3-6-22-10-11)16-15(9-12)24-17(25-16)14-5-1-2-7-23-14/h1-10H,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Patent Foundation US Patent					Assay Description We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...				US Patent US8748618 (2014) BindingDB Entry DOI: 10.7270/Q25M64C7
					More data for this Ligand-Target Pair