BDBM123681 US8748618, AI-10-87

SMILES: COCCOc1ccc(nc1)-c1nc2ccc(OC(F)(F)F)cc2[nH]1

InChI Key: InChIKey=QUHZPVGXUMNKLN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123681   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Core-binding factor subunit beta (CBFB) (Homo sapiens (Human))	BDBM123681 (US8748618, AI-10-87) Show SMILES COCCOc1ccc(nc1)-c1nc2ccc(OC(F)(F)F)cc2[nH]1 Show InChI InChI=1S/C16H14F3N3O3/c1-23-6-7-24-11-3-5-13(20-9-11)15-21-12-4-2-10(8-14(12)22-15)25-16(17,18)19/h2-5,8-9H,6-7H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Patent Foundation US Patent					Assay Description We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...				US Patent US8748618 (2014) BindingDB Entry DOI: 10.7270/Q25M64C7
					More data for this Ligand-Target Pair