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SMILES: Fc1cccnc1-c1nc2ccc(OC(F)(F)F)cc2[nH]1

InChI Key: InChIKey=AJBCOCZSWAXLPI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123683   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Core-binding factor subunit beta


(Homo sapiens (Human))		BDBM123683
PNG
(US8748618, AI-10-65)
Show SMILES Fc1cccnc1-c1nc2ccc(OC(F)(F)F)cc2[nH]1
Show InChI InChI=1S/C13H7F4N3O/c14-8-2-1-5-18-11(8)12-19-9-4-3-7(6-10(9)20-12)21-13(15,16)17/h1-6H,(H,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 2.20E+4n/an/an/an/an/an/a



University of Virginia Patent Foundation

US Patent


Assay Description
We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...

US Patent US8748618 (2014)


BindingDB Entry DOI: 10.7270/Q25M64C7
More data for this
Ligand-Target Pair