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SMILES: Cc1[nH]nc(N)c1-c1nc2cc(F)c(cc2s1)S(=O)(=O)NCCO

InChI Key: InChIKey=FPJDFJGMHIJACK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123946   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrin-linked protein kinase


(Homo sapiens (Human))		BDBM123946
PNG
(US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-5-...)
Show SMILES Cc1[nH]nc(N)c1-c1nc2cc(F)c(cc2s1)S(=O)(=O)NCCO
Show InChI InChI=1S/C13H14FN5O3S2/c1-6-11(12(15)19-18-6)13-17-8-4-7(14)10(5-9(8)23-13)24(21,22)16-2-3-20/h4-5,16,20H,2-3H2,1H3,(H3,15,18,19)
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Similars
US Patent
n/an/a 50n/an/an/an/an/a40



Dermira (Canada), Inc.

US Patent


Assay Description
5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...

US Patent US8754233 (2014)


BindingDB Entry DOI: 10.7270/Q23N2231
More data for this
Ligand-Target Pair