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BDBM123948 US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazol-5-ol

SMILES: Cc1[nH]nc(N)c1-c1nc2cc(O)ccc2s1

InChI Key: InChIKey=DXZQRFSKAGSMFH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123948   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase ILK-1


(Homo sapiens (Human))
BDBM123948
PNG
(US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-be...)
Show SMILES Cc1[nH]nc(N)c1-c1nc2cc(O)ccc2s1
Show InChI InChI=1S/C11H10N4OS/c1-5-9(10(12)15-14-5)11-13-7-4-6(16)2-3-8(7)17-11/h2-4,16H,1H3,(H3,12,14,15)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 200n/an/an/an/an/a40



Dermira (Canada), Inc.

US Patent


Assay Description
5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...


US Patent US8754233 (2014)


BindingDB Entry DOI: 10.7270/Q23N2231
More data for this
Ligand-Target Pair