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SMILES: Cc1[nH]nc(N)c1-c1nc2ccc(cc2s1)S(=O)(=O)NCC(F)(F)F

InChI Key: InChIKey=WNAMZFOXKDMWAL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123962   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrin-linked protein kinase


(Homo sapiens (Human))		BDBM123962
PNG
(US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-be...)
Show SMILES Cc1[nH]nc(N)c1-c1nc2ccc(cc2s1)S(=O)(=O)NCC(F)(F)F
Show InChI InChI=1S/C13H12F3N5O2S2/c1-6-10(11(17)21-20-6)12-19-8-3-2-7(4-9(8)24-12)25(22,23)18-5-13(14,15)16/h2-4,18H,5H2,1H3,(H3,17,20,21)
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Similars
US Patent
n/an/a 90n/an/an/an/an/a40



Dermira (Canada), Inc.

US Patent


Assay Description
5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...

US Patent US8754233 (2014)


BindingDB Entry DOI: 10.7270/Q23N2231
More data for this
Ligand-Target Pair