BDBM123965 US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid(pyridin-4-ylmethyl)-amide

SMILES: Cc1[nH]nc(N)c1-c1nc2ccc(cc2s1)S(=O)(=O)NCc1ccncc1

InChI Key: InChIKey=BPOYLASJFDENBE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123965   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin-linked protein kinase (Homo sapiens (Human))	BDBM123965 (US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-be...) Show SMILES Cc1[nH]nc(N)c1-c1nc2ccc(cc2s1)S(=O)(=O)NCc1ccncc1 Show InChI InChI=1S/C17H16N6O2S2/c1-10-15(16(18)23-22-10)17-21-13-3-2-12(8-14(13)26-17)27(24,25)20-9-11-4-6-19-7-5-11/h2-8,20H,9H2,1H3,(H3,18,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	40
Dermira (Canada), Inc. US Patent					Assay Description 5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...				US Patent US8754233 (2014) BindingDB Entry DOI: 10.7270/Q23N2231
					More data for this Ligand-Target Pair