BDBM123993 US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl)-5-isoxazol-5-yl-2H-pyrazol-3-ylamine

SMILES: COc1cc2sc(nc2cc1F)-c1c(N)[nH]nc1-c1ccno1

InChI Key: InChIKey=YKXDFTUXTJQUSR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123993   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin-linked protein kinase (Homo sapiens (Human))	BDBM123993 (US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl...) Show SMILES COc1cc2sc(nc2cc1F)-c1c(N)[nH]nc1-c1ccno1 Show InChI InChI=1S/C14H10FN5O2S/c1-21-9-5-10-7(4-6(9)15)18-14(23-10)11-12(19-20-13(11)16)8-2-3-17-22-8/h2-5H,1H3,(H3,16,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	40
Dermira (Canada), Inc. US Patent					Assay Description 5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...				US Patent US8754233 (2014) BindingDB Entry DOI: 10.7270/Q23N2231
					More data for this Ligand-Target Pair