BDBM124008 US8754233, 4-(6-Dimethylaminomethyl-benzothiazol-2-yl)-5-methyl-2H-pyrazol-3-ylamine

SMILES: CN(C)Cc1ccc2nc(sc2c1)-c1c(C)[nH]nc1N

InChI Key: InChIKey=IUINLGIEEUGQST-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124008   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin-linked protein kinase (Homo sapiens (Human))	BDBM124008 (US8754233, 4-(6-Dimethylaminomethyl-benzothiazol-2...) Show SMILES CN(C)Cc1ccc2nc(sc2c1)-c1c(C)[nH]nc1N Show InChI InChI=1S/C14H17N5S/c1-8-12(13(15)18-17-8)14-16-10-5-4-9(7-19(2)3)6-11(10)20-14/h4-6H,7H2,1-3H3,(H3,15,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	40
Dermira (Canada), Inc. US Patent					Assay Description 5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...				US Patent US8754233 (2014) BindingDB Entry DOI: 10.7270/Q23N2231
					More data for this Ligand-Target Pair