BDBM124022 US8754233, 4-Benzothiazol-2-yl-5-(3-methylamino-propyl)-2H-pyrazol-3-ylamine

SMILES: CNCCCc1[nH]nc(N)c1-c1nc2ccccc2s1

InChI Key: InChIKey=AUVSEZNSBWGOIM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124022   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase ILK-1 (Homo sapiens (Human))	BDBM124022 (US8754233, 4-Benzothiazol-2-yl-5-(3-methylamino-pr...) Show SMILES CNCCCc1[nH]nc(N)c1-c1nc2ccccc2s1 Show InChI InChI=1S/C14H17N5S/c1-16-8-4-6-10-12(13(15)19-18-10)14-17-9-5-2-3-7-11(9)20-14/h2-3,5,7,16H,4,6,8H2,1H3,(H3,15,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	40
Dermira (Canada), Inc. US Patent					Assay Description 5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...				US Patent US8754233 (2014) BindingDB Entry DOI: 10.7270/Q23N2231
					More data for this Ligand-Target Pair