BDBM1241 (Hydroxyethyl)amidosuccinoyl deriv. 13::benzyl N-[(2S,3R)-4-[(2R)-2-tert-butyl-N-cyclohexylbutanediamido]-3-hydroxy-1-phenylbutan-2-yl]carbamate

SMILES: CC(C)(C)[C@@H](CC(=O)NC1CCCCC1)C(=O)NC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key: InChIKey=DKGUABRGUNATNU-HZFUHODCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1241   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIV-1 Protease (Human immunodeficiency virus type 1)	BDBM1241 ((Hydroxyethyl)amidosuccinoyl deriv. 13 | benzyl N-...) Show SMILES CC(C)(C)[C@@H](CC(=O)NC1CCCCC1)C(=O)NC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C32H45N3O5/c1-32(2,3)26(20-29(37)34-25-17-11-6-12-18-25)30(38)33-21-28(36)27(19-23-13-7-4-8-14-23)35-31(39)40-22-24-15-9-5-10-16-24/h4-5,7-10,13-16,25-28,36H,6,11-12,17-22H2,1-3H3,(H,33,38)(H,34,37)(H,35,39)/t26-,27-,28+/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	135	n/a	n/a	n/a	n/a	5.5	37
Boehringer Ingelheim (Canada) Ltd.					Assay Description Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Cleavage products and substrate w...				J Med Chem 40: 2164-76 (1997) Article DOI: 10.1021/jm9606608 BindingDB Entry DOI: 10.7270/Q2R20ZJW
					More data for this Ligand-Target Pair