BDBM124196 US8748451, 12

SMILES: ONC(=O)c1ccc(CCn2c3ccccc3c3ccccc23)cc1

InChI Key: InChIKey=VMOPUWFBSOHSLH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 124196   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM124196 (US8748451, 12) Show SMILES ONC(=O)c1ccc(CCn2c3ccccc3c3ccccc23)cc1 Show InChI InChI=1S/C21H18N2O2/c24-21(22-25)16-11-9-15(10-12-16)13-14-23-19-7-3-1-5-17(19)18-6-2-4-8-20(18)23/h1-12,25H,13-14H2,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	8.0	25
The Board of Trustees of The University of Illinois US Patent					Assay Description HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...				US Patent US8748451 (2014) BindingDB Entry DOI: 10.7270/Q26D5RPK
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM124196 (US8748451, 12) Show SMILES ONC(=O)c1ccc(CCn2c3ccccc3c3ccccc23)cc1 Show InChI InChI=1S/C21H18N2O2/c24-21(22-25)16-11-9-15(10-12-16)13-14-23-19-7-3-1-5-17(19)18-6-2-4-8-20(18)23/h1-12,25H,13-14H2,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	8.0	25
The Board of Trustees of The University of Illinois US Patent					Assay Description HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...				US Patent US8748451 (2014) BindingDB Entry DOI: 10.7270/Q26D5RPK
					More data for this Ligand-Target Pair