BDBM124243 N,N'-([1,1'-biphenyl]-4,4'-diyl)bis(1-(3-methylbutanoyl)piperidine-4-carboxamide) (17)

SMILES: CC(C)CC(=O)N1CCC(CC1)C(=O)Nc1ccc(cc1)-c1ccc(NC(=O)C2CCN(CC2)C(=O)CC(C)C)cc1

InChI Key: InChIKey=NUPRKZYZYMKRKO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124243   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM124243 (N,N'-([1,1'-biphenyl]-4,4'-diyl)bis(1-...) Show SMILES CC(C)CC(=O)N1CCC(CC1)C(=O)Nc1ccc(cc1)-c1ccc(NC(=O)C2CCN(CC2)C(=O)CC(C)C)cc1 Show InChI InChI=1S/C34H46N4O4/c1-23(2)21-31(39)37-17-13-27(14-18-37)33(41)35-29-9-5-25(6-10-29)26-7-11-30(12-8-26)36-34(42)28-15-19-38(20-16-28)32(40)22-24(3)4/h5-12,23-24,27-28H,13-22H2,1-4H3,(H,35,41)(H,36,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jiangnan University					Assay Description IC50 values were determined by pNPP assay.				Bioorg Med Chem Lett 24: 1889-94 (2014) Article DOI: 10.1016/j.bmcl.2014.03.015 BindingDB Entry DOI: 10.7270/Q2PC3122
					More data for this Ligand-Target Pair