BDBM124264 Bis(4-nitro-2-((phenylimino)methyl)phenolate)-oxovanadium(IV) (5)
SMILES: [O-][N+](=O)c1ccc2O[V]3(=O)(Oc4ccc(cc4C=[N]3c3ccccc3)[N+]([O-])=O)[N](=Cc2c1)c1ccccc1
InChI Key: InChIKey=CQZKRCOWOCIEML-YOMCRPSHSA-L
Data: 5 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein-tyrosine phosphatase 1B (Homo sapiens (Human)) | BDBM124264 (Bis(4-nitro-2-((phenylimino)methyl)phenolate)-oxov...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 930 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Shanxi University | Assay Description The assays were performed in 20 mM MOPS buffer, pH 7.2, containing 50 mM NaCl and 2 mM GSH. Compounds were dissolved in DMSO and diluted to various c... | Dalton Trans 41: 11116-24 (2012) Article DOI: 10.1039/c2dt30198a BindingDB Entry DOI: 10.7270/Q2DZ070W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human)) | BDBM124264 (Bis(4-nitro-2-((phenylimino)methyl)phenolate)-oxov...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Shanxi University | Assay Description The assays were performed in 20 mM MOPS buffer, pH 7.2, containing 50 mM NaCl and 2 mM GSH. Compounds were dissolved in DMSO and diluted to various c... | Dalton Trans 41: 11116-24 (2012) Article DOI: 10.1039/c2dt30198a BindingDB Entry DOI: 10.7270/Q2DZ070W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human)) | BDBM124264 (Bis(4-nitro-2-((phenylimino)methyl)phenolate)-oxov...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Shanxi University | Assay Description The assays were performed in 20 mM MOPS buffer, pH 7.2, containing 50 mM NaCl and 2 mM GSH. Compounds were dissolved in DMSO and diluted to various c... | Dalton Trans 41: 11116-24 (2012) Article DOI: 10.1039/c2dt30198a BindingDB Entry DOI: 10.7270/Q2DZ070W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-tyrosine phosphatase 1C (Homo sapiens (Human)) | BDBM124264 (Bis(4-nitro-2-((phenylimino)methyl)phenolate)-oxov...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Shanxi University | Assay Description The assays were performed in 20 mM MOPS buffer, pH 7.2, containing 50 mM NaCl and 2 mM GSH. Compounds were dissolved in DMSO and diluted to various c... | Dalton Trans 41: 11116-24 (2012) Article DOI: 10.1039/c2dt30198a BindingDB Entry DOI: 10.7270/Q2DZ070W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Megakaryocyte protein-tyrosine phosphatase (PTP-MEG2) (Homo sapiens (Human)) | BDBM124264 (Bis(4-nitro-2-((phenylimino)methyl)phenolate)-oxov...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Shanxi University | Assay Description The assays were performed in 20 mM MOPS buffer, pH 7.2, containing 50 mM NaCl and 2 mM GSH. Compounds were dissolved in DMSO and diluted to various c... | Dalton Trans 41: 11116-24 (2012) Article DOI: 10.1039/c2dt30198a BindingDB Entry DOI: 10.7270/Q2DZ070W | |||||||||||
More data for this Ligand-Target Pair |