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BDBM124806 US8759386, 3

SMILES: Cc1nn(Cc2ccc(NC(=O)c3cc4ccccc4n3Cc3ccccc3)cc2F)c(C)c1CC(O)=O

InChI Key: InChIKey=TVECYMUPQLGJFU-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124806   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM124806
PNG
(US8759386, 3)
Show SMILES Cc1nn(Cc2ccc(NC(=O)c3cc4ccccc4n3Cc3ccccc3)cc2F)c(C)c1CC(O)=O
Show InChI InChI=1S/C30H27FN4O3/c1-19-25(16-29(36)37)20(2)35(33-19)18-23-12-13-24(15-26(23)31)32-30(38)28-14-22-10-6-7-11-27(22)34(28)17-21-8-4-3-5-9-21/h3-15H,16-18H2,1-2H3,(H,32,38)(H,36,37)
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Similars

US Patent
0.200n/an/an/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...


Citation and Details
More data for this
Ligand-Target Pair