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BDBM124817 US8759386, 14

SMILES: COc1ccc2[nH]c(C(=O)Nc3ccc(Cn4nc(C)c(CC(O)=O)c4C)cc3)c(C)c2c1

InChI Key: InChIKey=KYUYLIFDWRDPKP-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124817   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM124817
PNG
(US8759386, 14)
Show SMILES COc1ccc2[nH]c(C(=O)Nc3ccc(Cn4nc(C)c(CC(O)=O)c4C)cc3)c(C)c2c1
Show InChI InChI=1S/C25H26N4O4/c1-14-20-11-19(33-4)9-10-22(20)27-24(14)25(32)26-18-7-5-17(6-8-18)13-29-16(3)21(12-23(30)31)15(2)28-29/h5-11,27H,12-13H2,1-4H3,(H,26,32)(H,30,31)
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Similars

US Patent
0.100n/an/an/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...


Citation and Details
More data for this
Ligand-Target Pair