BDBM124817 US8759386, 14

SMILES: COc1ccc2[nH]c(C(=O)Nc3ccc(Cn4nc(C)c(CC(O)=O)c4C)cc3)c(C)c2c1

InChI Key: InChIKey=KYUYLIFDWRDPKP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124817   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM124817 (US8759386, 14) Show SMILES COc1ccc2[nH]c(C(=O)Nc3ccc(Cn4nc(C)c(CC(O)=O)c4C)cc3)c(C)c2c1 Show InChI InChI=1S/C25H26N4O4/c1-14-20-11-19(33-4)9-10-22(20)27-24(14)25(32)26-18-7-5-17(6-8-18)13-29-16(3)21(12-23(30)31)15(2)28-29/h5-11,27H,12-13H2,1-4H3,(H,26,32)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	-13.6	n/a	n/a	n/a	n/a	n/a	7.4	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8759386 (2014) BindingDB Entry DOI: 10.7270/Q2S46QM5
					More data for this Ligand-Target Pair