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SMILES: CCc1nn(Cc2ccc(NC(=O)c3cc4cc(Cl)ccc4o3)cc2)c(CC)c1CC(O)=O

InChI Key: InChIKey=OCIMRIZREBTKBR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124822   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM124822
PNG
(US8759386, 19)
Show SMILES CCc1nn(Cc2ccc(NC(=O)c3cc4cc(Cl)ccc4o3)cc2)c(CC)c1CC(O)=O
Show InChI InChI=1S/C25H24ClN3O4/c1-3-20-19(13-24(30)31)21(4-2)29(28-20)14-15-5-8-18(9-6-15)27-25(32)23-12-16-11-17(26)7-10-22(16)33-23/h5-12H,3-4,13-14H2,1-2H3,(H,27,32)(H,30,31)
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Similars
US Patent
 0.200 -13.2n/an/an/an/an/a7.425



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...

US Patent US8759386 (2014)


BindingDB Entry DOI: 10.7270/Q2S46QM5
More data for this
Ligand-Target Pair