BDBM124831 US8759386, 28

SMILES: CCCn1c(cc2ccc(F)cc12)C(=O)Nc1ccc(Cn2nc(C)c(CC(O)=O)c2C)cc1

InChI Key: InChIKey=RJRCNMWOPDGPKF-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124831   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM124831 (US8759386, 28) Show SMILES CCCn1c(cc2ccc(F)cc12)C(=O)Nc1ccc(Cn2nc(C)c(CC(O)=O)c2C)cc1 Show InChI InChI=1S/C26H27FN4O3/c1-4-11-30-23-13-20(27)8-7-19(23)12-24(30)26(34)28-21-9-5-18(6-10-21)15-31-17(3)22(14-25(32)33)16(2)29-31/h5-10,12-13H,4,11,14-15H2,1-3H3,(H,28,34)(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	-13.6	n/a	n/a	n/a	n/a	n/a	7.4	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8759386 (2014) BindingDB Entry DOI: 10.7270/Q2S46QM5
					More data for this Ligand-Target Pair