BDBM124834 US8759386, 31

SMILES: CCn1c(cc2ccccc12)C(=O)Nc1ccc(Cn2nc(C)c(CC(O)=O)c2C)c(F)c1

InChI Key: InChIKey=KOWYGQLUFIKFQX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124834   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM124834 (US8759386, 31) Show SMILES CCn1c(cc2ccccc12)C(=O)Nc1ccc(Cn2nc(C)c(CC(O)=O)c2C)c(F)c1 Show InChI InChI=1S/C25H25FN4O3/c1-4-29-22-8-6-5-7-17(22)11-23(29)25(33)27-19-10-9-18(21(26)12-19)14-30-16(3)20(13-24(31)32)15(2)28-30/h5-12H,4,13-14H2,1-3H3,(H,27,33)(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	-13.2	n/a	n/a	n/a	n/a	n/a	7.4	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8759386 (2014) BindingDB Entry DOI: 10.7270/Q2S46QM5
					More data for this Ligand-Target Pair